Plant Transcription Factor Database
Previous version: v3.0
Nicotiana benthamiana
NF-YA Family
Species TF ID Description
Niben101Scf00088g01008.1NF-YA family protein
Niben101Scf00736g01012.1NF-YA family protein
Niben101Scf00781g06015.1NF-YA family protein
Niben101Scf00911g01003.1NF-YA family protein
Niben101Scf01429g01013.1NF-YA family protein
Niben101Scf01796g01001.1NF-YA family protein
Niben101Scf02425g01005.1NF-YA family protein
Niben101Scf02790g03007.1NF-YA family protein
Niben101Scf04323g04020.1NF-YA family protein
Niben101Scf04869g07001.1NF-YA family protein
Niben101Scf04921g00005.1NF-YA family protein
Niben101Scf05694g00003.1NF-YA family protein
Niben101Scf05919g00004.1NF-YA family protein
Niben101Scf09296g01011.1NF-YA family protein
Niben101Scf10191g01007.1NF-YA family protein
Niben101Scf10498g01001.1NF-YA family protein
Niben101Scf13231g00006.1NF-YA family protein
Niben101Scf13387g00028.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982